Goat Secondary Antibodies
Cayman Chemical ChlorogenIc AcId 1g
Chlorogenic acid is a phenolic natural product isolated from the leaves and fruits of dicotyledonous plants, including the coffee bean. Structurally, chlorogenic acid is the ester of caffeic acid with the 3-hydroxyl group of quinic acid. Chlorogenic acid is an important factor in plant metabolism. It is also an antioxidant and an inhibitor of the tumor promoting activity of phorbol esters.{1430,1420} Chlorogenic acid, at concentrations as high as 100 µM, does not inhibit the 5-LO activity of ionophore-stimulated human PMNL.{4706}
Cayman Chemical DIgItls pururea DIgItIn 250mg
A non-ionic detergent used to solubilize membrane-bound proteins, to precipitate cholesterol, and to permeabilize cell membranes
ABclonal Technology MEF2C Rabbit pAb
This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.
ABclonal Technology VEGFA Rabbit pAb
This gene belongs to the PDGF/VEGF growth factor family and encodes a heparin-binding homodimeric protein essential for angiogenesis. It promotes vascular endothelial cell proliferation and migration. Disruption in mice impairs embryonic blood vessel formation. The gene is upregulated in many tumors, correlating with tumor stage, and is elevated in POEMS syndrome. Variants are linked to diabetic microvascular complications and atherosclerosis. Multiple isoforms arise from alternative splicing, translation initiation, and stop codon readthrough; one extended isoform is antiangiogenic. Expression is also regulated by an upstream ORF within an IRES. VEGF levels rise during SARS-CoV-2 infection, promoting inflammation and a feedback loop involving Ang II and cytokine release.
Cayman Chemical Fonculum vulga Mlntol 250g
A phenylpropanoid with antifungal and antioxidant activity; active against fermentatively growing S. cerevisiae under hypoxic, but not normoxic, conditions (MIC = 100 UG/ml), and against C. parapsilosis at 15% w/w; has antioxidant activity in a TEAC assay but does not scavenge DPPH radicals in a cell-free assay
Cayman Chemical R4AmIno3hydroxybutyrIc 250mg
A GABA receptor modulator; binds to GABAA and GABAB receptors (IC50s = 1 and 0.35 µM, respectively); inhibits GABA uptake in rat brain synaptosomes (IC50 = 67 µM); induces currents in a patch-clamp assay using Xenopus oocytes expressing human GABAC (EC50 = 19 µM); inhibits electrical discharges in the amygdala in a cat model of N-amidinobenzamide-induced seizures at 20 mg/animal
Cayman Chemical cPP1-7 NPY19-23 Ala31 AIb325mg
An agonist of NPY receptor Y5; inhibits forskolin-induced cAMP production in HEK293 cells expressing the Y5 receptor (EC50 = 17 nM); selectively binds to Y5 (IC50 = 0.24 nM in HEK293 cells expressing the human receptor) over Y1, Y2, and Y4 (IC50s = 530, >500, and 51 nM, respectively, in BHK-21 cells expressing the human receptors); increases VEGF levels, as well as endothelial branch length and branch points, in 4T1 cells in a concentration-dependent manner; induces relaxation of vasopressin-precontracted rat mesenteric arteries at 1 µM; increases food intake in rats at 0.2 and 2 nmol/animal, i.c.v.
Biolegend Spark PLUS B550TM anti-human C
Spark PLUS B550™ anti-human CD137 (4-1BB) [S18014C]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests
ABclonal Technology PEDF/SERPINF1 Rabbit pAb
This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI.
ABclonal Technology HDGF Rabbit pAb
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.
American Research Products Inc MK4830 Biosimialr Biosimilar
MK-4830 Biosimialr Biosimilar (Anti-LILRB2) Antibody is a biosimilar antibody with human reactivity produced in humanized Available in 100 ug size with 7 - 14 business days lead time Ships via gel pack Store at -20 C to -80 C for 12 months in lyophilized form After reconstitution if not intended for use within a month aliquot and store at -80 C (Avoid repeated freezing and thawing) Lyophilized antibodies are shipped at ambient temperature
Cayman Chemical DIhydrocaffeIc AcId 25g
A polyphenol; scavenges ABTS (IC50 = 81.86 μg/ml) and DPPH (IC50 = 192.86 μg/ml) radicals; increases the survival of RGC-5 mouse retinal ganglion cells under hypoxic conditions and in the presence of SNAP in a concentration-dependent manner; decreases eNOS activity in EA.hy926 human endothelial cells in a concentration-dependent manner; decreases infarct size in a rat model of transient ischemia induced by MCAO at 30 mg/kg
ABclonal Technology BET1 Rabbit pAb
This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex. The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein receptor and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternative splicing results in multiple transcript variants.
Cayman Chemical HentrIacontn 500mg
An alkane with anti-inflammatory activity; reduces LPS-induced TNF-α, IL-6, and IL-1β production in RAW 264.7 cells; reduces LPS-induced TNF-α, IL-6 and IL-1β production in whole blood and carrageenan-induced paw edema in mice